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Ӳ֬øAȥøSCDERĤף߻ɱ֬γɵ֬ᡣоSCDлĹؼӣѪ֬쳣ͷӰ졣Ӳ֬øAγ˫ɱ֬Ӳ֬֬ķӲ֬øAȥøһֺø߻֬ϳеٲ衣 SCDҪᣬͨӲ֬ȥγɡӲ֬ıͨϸĤԺźתӰ漰ϸͷֻĵڡ


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15-PGDH 5 alphaԭø 5֬ø øAȻø תø Ѱø ռø ȩø(ALDH) ȩǻԭø ø Ѫܽתø(ACE) ATGL ATPѽø ̼ø ֯ø CETP COMT ϸɫP450 Ļø Ͱ-ǻø E1/E2/E3ø Եø ϩø FAAH FABP Xa ػתø ֬ϳø(FAS) FXR Ǽø GSNOR ׸S-תø HCVø Ǽø HIF/HIF-ǻø ̲ø HIVø HMG-CoAԭø(HMGCR) HSP ᰷2,3-ø(IDO) ø(IDH) ø LXR MAGL Ƥʼ л MMP NAMPT NEDD8ø Էø PAI-1 PDHK PGC-1 ø ø(PDE) ֬ ǰԭCø ø ͪἤø RAR/RXR ROR Ser/Thrø SGK Ӳ֬øAȥø(SCD) Ѫø ɫǻø Ұø ø
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ۼ Ƽ/ERR м ״ټ

MF-438

MF-438 һЧҿڷõ stearoyl-CoA desaturase 1 (SCD1) Ƽ rSCD1 EC50 ֵΪ 2.3 nM

  • CASţ921605-87-0
  • ʽC19H18F3N5OS
  • 421.44
  • Ӳ֬øAȥø(SCD)
  • ܶȣN/A
  • е㣺N/A
  • ۵㣺N/A
  • 㣺N/A
۸

4-(2-ȱ)-N-[3-[(װ)ʻ]]-1-Ȱ

A939572 һֿڷЧ SCD1 Ƽ mSCD1 hSCD1IC50 ֱΪ <4 nM 37 nM

  • CASţ1032229-33-6
  • ʽC20H22ClN3O3
  • 387.86000
  • Ӳ֬øAȥø(SCD)
  • ܶȣ1.302 g/cm3
  • е㣺633.5C at 760 mmHg
  • ۵㣺N/A
  • 㣺336.9C
۸

T-3764518

T-3764518 ӱЧӲ֬øAȥø (SCD) ƼIC50 Ϊ4.7 nM

  • ܶȣN/A
  • е㣺N/A
  • ۵㣺N/A
  • 㣺N/A
۸

GSK1940029

SCD inhibitor 1 һЧ-øAȥø (SCD) ƼϸϢοר WO/2009060053 A1 еĻ example 16

  • CASţ1150701-66-8
  • ʽC18H16Cl2N4O2
  • 391.251
  • Ӳ֬øAȥø(SCD)
  • ܶȣ1.40.1 g/cm3
  • е㣺N/A
  • ۵㣺N/A
  • 㣺N/A
۸

4- 2-

PluriSln 1 һ-øAȥø (SCD) ƼһֶϸԵƼ

  • CASţ91396-88-2
  • ʽC12H11N3O
  • 213.235
  • Ӳ֬øAȥø(SCD)
  • ܶȣ1.30.1 g/cm3
  • е㣺335.715.0 C at 760 mmHg
  • ۵㣺177-178
  • 㣺156.920.4 C
۸

Elemicin һϩ㷺ֲҩСElemicin ͨлӲ֬ø A ȥø 1 (SCD1)Elemicin ǷʳƷеҪɷ֮һп΢ͿԡElemicin ŴԺ°ԡ

  • CASţ487-11-6
  • ʽC12H16O3
  • 208.25400
  • Ӳ֬øAȥø(SCD)
  • ܶȣ1.011 g/cm3
  • е㣺279.8C at 760 mmHg
  • ۵㣺N/A
  • 㣺92.6C
۸

XEN723

XEN723 һЧӲ֬ø A ȥø (SCD1) ͪƼС HepG2 ϸе IC50 ֱֵΪ 45 524 nM

  • ܶȣN/A
  • е㣺N/A
  • ۵㣺N/A
  • 㣺N/A
۸

MK-8245

MK-8245ǸΰӲ֬-CoAȥøSCDƼSCD1SCD1IC50ֱΪ1 nM3 nM

  • CASţ1030612-90-8
  • ʽC17H16BrFN6O4
  • 467.249
  • Ӳ֬øAȥø(SCD)
  • ܶȣ1.80.1 g/cm3
  • е㣺698.365.0 C at 760 mmHg
  • ۵㣺N/A
  • 㣺376.134.3 C
۸

SCD1Ƽ-1

SCD1 inhibitor-1 ЧΰӲ֬ -CoA ȥø (SCD1) Ƽ

  • CASţ1069094-65-0
  • ʽC21H22N3NaO3S2
  • 451.54
  • Ӳ֬øAȥø(SCD)
  • ܶȣN/A
  • е㣺N/A
  • ۵㣺N/A
  • 㣺N/A
۸

MK-8245

MK-8245ǸΰӲ֬-CoAȥøSCDƼSCD1SCD1IC50ֱΪ1 nM3 nM

  • CASţ1415559-41-9
  • ʽC19H17BrF4N6O6
  • 581.27200
  • Ӳ֬øAȥø(SCD)
  • ܶȣN/A
  • е㣺N/A
  • ۵㣺N/A
  • 㣺N/A
۸

CVT-12012

CVT-12012 һЧġпڷԵӲ֬-CoA ȥø (SCD) ƼԴ΢ HEPG2 IC50 ֱֵΪ 38 nM6.1 nM

  • CASţ1018675-35-8
  • ʽC21H21F3N4O3
  • 434.41200
  • Ӳ֬øAȥø(SCD)
  • ܶȣN/A
  • е㣺N/A
  • ۵㣺N/A
  • 㣺N/A
۸

CAY10566

CAY10566 һӲ֬ø A ȥø (SCD) Ƽ

  • CASţ944808-88-2
  • ʽC18H17ClFN5O2
  • 389.811
  • Ӳ֬øAȥø(SCD)
  • ܶȣ1.40.1 g/cm3
  • е㣺600.265.0 C at 760 mmHg
  • ۵㣺N/A
  • 㣺316.834.3 C
۸